Wednesday, 26 June 2013

Can You Assess Diabetic Complications before it actually occurs?

Can You Assess Diabetic Complications before it actually occurs?
Yes/ Most Likely.
Risk of Diabetes
In 1993, most popular Diabetic Control & Complication Trail study (conducted in USA) showed for the first time that strict control in patients with type-1 diabetes greatly reduced the complication of the disease, and United Kingdom Prospective Diabetes Study proved similar evidence in favour of strict control in patient with type-2 diabetes.
Both the studies stressed on quantifying the complications as earliest possible, because once a macro or micro vascular diabetic complications take place, then quality of life gets affected at different levels directly or indirectly. Diabetic complications are:

First- cause of increased expenses and unending pain
Second- cause/risk of physical disability
Third- increased risk of death.

Decontrol or poor blood sugar control is main reason for all diabetic complications, it causes fix by the Global scientists are – Lack of awareness of diabetes, avoid pathological tests, Self- medication, poor compliance (including diet & exercise), unable to differentiate between control and cure, and finally patient don’t want to know the severity, so patients are rarely involved when doctor are detailing about complications of diabetes. Resultant pressure on hospitals is increasing every day, rate of emergencies or mortality are now multi fold as compare to last 10 years.
To avoid these most complicated situation scientists of bio-medical field introduced new generation Non-invasive instruments working on a variable frequency (low to high) with built-in ECG capabilities and computer compatibility. These instruments measure R-R interval, Power-Spectrum, Poincare-plotting Pulse wave velocity, Arterial histogram, Arterial-brachial index, Cardio-techogram, valsalva manoeuvre (in graphical presentation) and Vibro-sensometry (for feet’s).
But output of above these instrumentation’s was again useful for doctors only, which patients were unable to understand, so they were not getting involved in this problem.
After a long exercise, we selected some pathological tests- Haemoglobin, haemtocrit, platelet count, lipids, SGOT, SGPT, ALP, Albumin, S.Urea, Creatinine, Uric acid, Calcium, Magnesium, Phosphors, Sodium, Potassium, Ghb1c, C-peptide, Insulin assay, and coordinate with above said instrumentation’s output and made very first time a new algorithm, and matched with patient complaints, the results were encouraging, and the important point was patient were understanding about their health status. We labelled it as 1st Diabetic Complication Assessment unit.
The comprehensive report assess risk of General health, function of pancreas and risk of eye, cardiovascular, cerbrovasculer, kidney, Impotency (sexual), neuropathic and feet.
For example- If a 35 yrs old, average weight, non alcoholic, non smoker has diabetes for last 1 year with diet control and regular exercise having, Ghb1c-8.5, C-peptide-1.4 and insulin-7.2, then his pancreatic function will be approximately 24.00% (Normal 100%). Interpretation- diet control and exercise are not sufficient, patient should be consult with diabetologist and switch over to anti-diabetic drug. It is very much useful to diabetologist, because most of the time diabetic patient are unable to explain their problems or new symptom in early stage, while the doctor are busy in his own schedule, so due to communication gap new symptoms gradually strengthen and get into a shape of severer diabetic complication.
A quick review of this report quantifying content tell the complete status of target organ, hint to modifying his treatment and reduced the cost of medication by 22-40%, reduced chance of OHGA failure, and hypoglycaemic bout of insulin.
By this Genetic Risk Assessment Scoring System approach a group of diabetic patients could understand what is their actual status of health due to diabetes, and start efforts for better control to push back diabetes complications, and:

Successfully improve their quality of life by 65-75%,
Reduce approximate cost of medication by 22-40%,
Reduce Risk of hospitalization by 45-50%,
Reduce the Complications by 55-60%,
Reduce the Risk of Emergency situations occurring due to diabetes by 60-65%,

The results will be seen not only on the individual but reduced emergency burden on hospitals, financial burden of individual as well as public and state run Government health programmes.
The GRASS-DIABETES is a different start in the field of diabetes, and helpful to doctors as well as patients.

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